I use my computer a lot. That is what bought it for. However there are ways to help keep it running well. By maintaining your computer the stress on the hardware is less, which in turn means your computer will probably last longer and operate better. If you know any other things to keep a mac running well please comment, as I am still a somewhat new to the mac scene.
1. Weekly Run of OnyX. I like OnyX because it is free, simple, and automated. I just let it do its thing. I highlight everything in the Automation Tab (Maintenance, Rebuilding, Cleaning). It takes a while, and afterwards the computer might run a bit slow for a while, because it is rebuilding a lot of indexes.
2. Weekly or Monthly Defragment. Since I am constantly Downloading, Uploading, Copying, Moving, and Deleting Files, my fragmentation will likely start to affect my hard drive’s performance. There is a huge debate all over the interwebs about if defragmentation is really needed for OS X. I feel that it is. What defragmentation does, is move files on the hard drive closer (and in better locations) so that the hard drive does not have to search for them all over the place. This will speed up performance and also keep your drive functioning longer. I am currently using the demo of Drive Genius 2 to do this.